Kisner registered his third PGA Tour victory by defeating Matt Kuchar, 3 and 2, in the championship match of the 2019 WGC-Dell Technologies Match Play at Austin (Texas) Country Club. It came a year after he lost in the championship match to Bubba Watson. His previous victory had come in the 2017 Dean & Deluca Invitational at Colonial Country Club. He was in a playoff at the 2015 Players Championship with Sergio Garcia and eventual winner Rickie Fowler. Kisner was a member of the 2005 NCAA championship team at the University of Georgia with fellow PGA Tour players Brendon Todd and Chris Kirk, along with 2001 U.S. Junior Amateur runner-up Richard Scott. He also has won twice on Web.com Tour. He represented the USA on the victorious 2017 Presidents Cup Team.