The South Carolina native won the 2009 U.S. Open at Bethpage Black, joining Michael Campbell (2005), Steve Jones (1996) and Jerry Pate (1976) as recent winners of the U.S. Open who went through final qualifying to win the championship. Glover owns six professional wins, three of which have come on the PGA Tour. His last win was in a playoff over fellow Clemson alum Jonathan Byrd in the 2011 Wells Fargo Championship. Glover was a member of the 2001 USA Walker Cup Team and played on the 2007 and 2009 USA Presidents Cup Teams.
U.S. Open Record
| Year | Site | Scores | To Par | Finish |
| 2020 | Winged Foot Golf Club (West Course) | 71-71-71-75--288 | +8 | T-17 |
| 2019 | Pebble Beach Golf Links | 73-72 | +3 | MC |
| 2018 | Shinnecock Hills Golf Club | 77-72 | +9 | MC |
| 2017 | Erin Hills | 74-72 | +2 | MC |
| 2016 | Oakmont Country Club | 75-74 | +9 | MC |
| 2015 | Chambers Bay | 73-83 | +16 | MC |
| 2014 | Pinehurst Resort & C.C. (Course No. 2) | 79-69 | +8 | MC |
| 2013 | Merion Golf Club | 74-82 | +16 | MC |
| 2012 | The Olympic Club | 76-73 | +9 | MC |
| 2011 | Congressional Country Club | 76-69-73-70--288 | +4 | T-42 |
| 2010 | Pebble Beach Golf Links | 73-73-77-76--299 | +15 | T-58 |
| 2009 | Bethpage State Park (Black Course) | 69-64-70-73--276 | -4 | Win |
| 2007 | Oakmont Country Club | 71-80 | +11 | MC |
| 2006 | Winged Foot Golf Club (West Course) | 75-77 | +12 | MC |
| 2002 | Bethpage State Park (Black Course) | 74-77 | +11 | MC |